Acute neurocognitive deficits in active duty service members following subconcussive blast exposure

被引:17
|
作者
Haran, F. J. [1 ,2 ,3 ]
Handy, Justin D. [4 ]
Servatius, Richard J. [4 ,5 ,6 ]
Rhea, Christopher K. [3 ]
Tsao, Jack W. [7 ,8 ,9 ]
机构
[1] Naval Med Res Ctr, Neurotrauma Dept, Silver Spring, MD USA
[2] Uniformed Serv Univ Hlth Sci, Dept Psychiat, Bethesda, MD 20814 USA
[3] Univ N Carolina, Dept Kinesiol, Greensboro, NC USA
[4] Stress & Motivated Behav Inst, Syracuse, NY USA
[5] Syracuse VA Med Ctr, Res & Dev, Syracuse, NY USA
[6] SUNY Upstate Med Univ, Dept Psychiat, Syracuse, NY 13210 USA
[7] Univ Tennessee, Ctr Hlth Sci, Dept Neurol, Memphis, TN 38163 USA
[8] Le Bonheur Childrens Hosp, Childrens Fdn Res Inst, Memphis, TN USA
[9] Memphis Vet Affairs Med Ctr, Dept Neurol, Memphis, TN USA
关键词
Blast injury; mild traumatic brain injury; military; neurocognitive; TRAUMATIC BRAIN-INJURY; LOW-LEVEL BLAST; COGNITIVE-BEHAVIORAL THERAPY; POST-CONCUSSIVE SYMPTOMS; SPORT-RELATED CONCUSSION; BASE-LINE; NEUROPSYCHOLOGICAL OUTCOMES; NORMATIVE COMPARISONS; CLINICAL-SIGNIFICANCE; OEF/OIF VETERANS;
D O I
10.1080/23279095.2019.1630627
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Military service members are frequently subjected to subconcussive blast events during training and deployment. Emerging evidence suggests blast exposures of these magnitudes may have long-term consequences for dimensions of cognitive function. Less is known about cognitive sequelae acutely following deployment-related subconcussive blast events. The current study addressed this knowledge gap by assessing the extent to which subconcussive blast exposure affected performance on the Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM). Baseline-referenced and normative comparisons of archival ANAM data were analyzed for a cohort of personnel who were exposed to blast (blast group; n = 27) and personnel who were not exposed to blast (no-blast group; n = 36) that were otherwise asymptomatic for a concussion. The blast group exhibited statistically significant lower scores compared to the no-blast group (between-subjects), baseline assessments (within-subjects), and an age-matched normative population. Normative comparisons revealed that the scores for the reaction time subtests (i.e., procedural and both simple reaction time tasks) were outside the range of normal functioning (1 SD) and reliable change indices revealed clinically meaningful change only for simple reaction time. The results highlight covert effects of subconcussive blast exposure that may warrant further monitoring in the immediate aftermath of a blast event.
引用
收藏
页码:297 / 309
页数:13
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