Interactive web-based identification and visualization of transcript shared sequences

被引：0
|
作者：
Azhir, Alaleh [1 ]
Merino, Louis-Henri [2 ]
Nauen, David W. [3 ]
机构：
[1] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD 21218 USA
[2] Univ Maryland, Dept Comp Sci, College Pk, MD 20742 USA
[3] Johns Hopkins Sch Med, Dept Pathol, Baltimore, MD 21205 USA
来源：
GENOMICS | 2019年 / 111卷 / 04期
关键词：
Alternative splicing; Splice variant; RNA; Visualization;
D O I：
10.1016/j.ygeno.2018.05.010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We have developed TraC (Transcript Consensus), a web-based tool for detecting and visualizing shared sequences among two or more mRNA transcripts such as splice variants. Results including exon-exon boundaries are returned in a highly intuitive, data-rich, interactive plot that permits users to explore the similarities and differences of multiple transcript sequences. The online tool (http://labs.pathology.jhu.edu/nauen/trac/) is free to use. The source code is freely available for download (https://github.com/nauenlab/TraC).
引用
收藏
页码：860 / 862
页数：3
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