Understanding Wax Printing: A Simple Micropatterning Process for Paper-Based Microfluidics

被引:1232
|
作者
Carrilho, Emanuel [1 ,2 ]
Martinez, Andres W. [1 ]
Whitesides, George M. [1 ]
机构
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
[2] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13566590 Sao Carlos, SP, Brazil
基金
比尔及梅琳达.盖茨基金会;
关键词
LOW-COST; DEVICES;
D O I
10.1021/ac901071p
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This technical note describes a detailed study on wax printing, a simple and inexpensive method for fabricating microfluidic devices in paper using a commercially available printer and hot plate. The printer prints patterns of solid wax on the surface of the paper, and the hot plate melts the wax so that it penetrates the full thickness of the paper. This process creates complete hydrophobic barriers in paper that define hydrophilic channels, fluid reservoirs, and reaction zones. The design of each device was based on a simple equation that accounts for the spreading of molten wax in paper.
引用
收藏
页码:7091 / 7095
页数:5
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