Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities

被引：4

作者：

Chen, Ying-Ying ^{[1
,2
]}

Hou, Jiang-Ping ^{[3
]}

Huang, Ling ^{[3
]}

Khan, Afsar ^{[4
]}

Xing, Fei-Fei ^{[2
]}

Zhang, Xiao-Han ^{[2
]}

Han, De-Feng ^{[2
]}

Yan, Shi-Li ^{[2
]}

Cao, Gui-Dong ^{[2
]}

Jiao, Qi-Yang ^{[2
]}

Liu, Dejie ^{[2
]}

Zhu, Xuwei ^{[2
]}

Hu, Qingwen ^{[2
]}

Lou, Hong-Xiang ^{[1
,2
]}

机构：

[1] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Key Lab Chem Biol,Minist Educ, Jinan, Peoples R China

[2] Reyoung Pharmaceut Co Ltd, Res & Dev Dept, Nat Prod Lab, Jinan, Peoples R China

[3] Shandong First Med Univ, Shandong Prov Hosp, Dept Ophthalmol, Jinan, Peoples R China

[4] COMSATS Univ Islamabad, Dept Chem, Abbottabad, Pakistan

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 08期

关键词：

Viscum coloratum; Santalaceae; diarylheptanoid; sesquiterpenoid; cytotoxic activity; ALBUM;

D O I：

10.1080/14786419.2020.1837816

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new diarylheptanoid, (1 R,2S,3S,5S)-2,3-dihydroxy-3',3''-dimethoxy-4'-de-O-methylcentrolobine (1) and a new bisabolane-type sesquiterpenoid, (1 R,7S)-1,12,13-trihydroxybisabola-3,10-diene (2), together with nineteen known compounds (3-21) were isolated from the EtOH extract of the stems and branches of Viscum coloratum (Kom.) Nakai. Their structures were elucidated by extensive analysis of 1 D and 2 D NMR spectra and from the HRESIMS. All the compounds were evaluated for their cytotoxic activity against eight human tumor cell lines.

引用

页码：1927 / 1933

页数：7

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