Design and synthesis of nuclear receptor antagonists targeting RARα for male contraception

被引:0
|
作者
Kyzer, Jillian [2 ]
Chen, Yan [1 ]
Cheryala, Narsimulu [2 ]
Cuellar, Rebecca [2 ]
Holth, Trinh [2 ]
Schonbrunn, Ernst [1 ]
Georg, Gunda [2 ]
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, SRB23005, Tampa, FL USA
[2] Univ Minnesota, Coll Pharm, Dept Med Chem, Room 452, Minneapolis, MN 55455 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
177
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Targeting nuclear receptor corepressors for reversible male contraception
    Hong, Suk - Hyun
    Castro, Glenda
    Wang, Dan
    Nofsinger, Russell
    Kane, Maureen
    Folias, Alexandra
    Atkins, Annette R.
    Yu, Ruth T.
    Napoli, Joseph L.
    Sassone-Corsi, Paolo
    de Rooij, Dirk G.
    Liddle, Christopher
    Downes, Michael
    Evans, Ronald M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 121 (09)
  • [2] Retinoic acid receptor antagonists for male contraception: current status
    Al Noman, Md Abdullah
    Kyzer, Jillian L.
    Chung, Sanny S. W.
    Wolgemuth, Debra J.
    Georg, Gunda, I
    BIOLOGY OF REPRODUCTION, 2020, 103 (02) : 390 - 399
  • [3] Design and synthesis of thrombin receptor antagonists
    Greenlee, William J.
    Chackalamannil, Samuel
    Wang, Yuguang
    Xia, Yan
    Clasby, Martin
    Eagen, Keith
    Tsai, Hsingan
    Gao, Xiaobang
    Boykow, George
    Chintala, Madhu
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [4] Design and synthesis of thrombin receptor antagonists
    Clasby, M
    Chackalamannil, S
    Czarnieckil, M
    Doller, D
    Eagen, K
    Greenlee, WJ
    Kao, G
    Lin, Y
    Tsai, H
    Xia, Y
    Agans-Fantuzzi, J
    Ahn, HS
    Boykow, G
    Bryant, M
    Chintala, M
    Foster, C
    Lau, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2572 - U2572
  • [5] Design of selective nuclear receptor modulators: RAR and RXR as a case study
    Angel R. de Lera
    William Bourguet
    Lucia Altucci
    Hinrich Gronemeyer
    Nature Reviews Drug Discovery, 2007, 6 : 811 - 820
  • [6] Design of selective nuclear receptor modulators: RAR and RXR as a case study
    de Lera, Angel R.
    Bourguet, William
    Altucci, Lucia
    Gronemeyer, Hinrich
    NATURE REVIEWS DRUG DISCOVERY, 2007, 6 (10) : 811 - 820
  • [7] Targeting A2A receptor to treat neurodegenerative diseases: design, synthesis and evaluation of potential antagonists
    Moas-Heloire, Valeria
    Renault, Nicolas
    Batalha, Vania L.
    Chavatte, Philippe
    Buee, Luc
    Blum, David
    Lopes, Luisa V.
    Agouridas, Laurence
    Melnyk, Patricia
    PURINERGIC SIGNALLING, 2014, 10 (04) : 769 - 770
  • [8] USE OF LHRH AGONISTS AND ANTAGONISTS IN MALE CONTRACEPTION - A REVIEW
    SUNDARAM, K
    CONTRACEPTION, 1984, 29 (02) : 163 - 170
  • [9] Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception
    Al Noman, Md Abdullah
    Cuellar, Rebecca A. D.
    Kyzer, Jillian L.
    Chung, Sanny S. W.
    Cheryala, Narsihmulu
    Holth, Trinh A. D.
    Maitra, Soma
    Naqvi, Tahmina
    Wong, Henry L.
    Schonbrunn, Ernst
    Hawkinson, Jon E.
    Wolgemuth, Debra J.
    Georg, Gunda I.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 261
  • [10] DESIGN AND SYNTHESIS OF ETA RECEPTOR ANTAGONISTS AND STUDY OF ETA RECEPTOR DISTRIBUTION
    KITADA, C
    OHTAKI, T
    MASUDA, Y
    MASUO, Y
    NOMURA, H
    ASAMI, T
    MATSUMOTO, Y
    SATOU, M
    FUJINO, M
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1993, 22 : S128 - S131