Engineering chemistry for the future of chemical synthesis

被引:61
|
作者
Fitzpatrick, D. E. [1 ]
Ley, S. V. [1 ]
机构
[1] Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England
基金
英国工程与自然科学研究理事会;
关键词
Continuous flow synthesis; Automation; Computer control; Machine-assisted synthesis; Future trends in synthesis; Lab of the future; CONTINUOUS-FLOW PROCESS; ONLINE IR ANALYSIS; REACTION OPTIMIZATION; SELF-OPTIMIZATION; ORGANIC-SYNTHESIS; ENABLING TECHNOLOGIES; MULTISTEP SYNTHESIS; REACTOR SYSTEM; PLATFORM; SCALE;
D O I
10.1016/j.tet.2017.08.050
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis is changing in response to our modern resource conscious world. The principles of green chemistry are evolving as the interfaces and boundaries in science are less obvious and providing a new stimuli for future discovery. The invention and application of new chemical reactivity continues to be a primary driver since this opens up so many strategic opportunities for synthesis. However, the manual intensive efforts behind such activity inevitably lead to the need for more machine based approaches. Indeed, the engineering of chemistry delineated in this Symposium in Print seeks to collate some of the recent progress and innovation in the area with contributions from its visionary practitioners. (C) 2017 Elsevier Ltd. All rights reserved.
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页码:3087 / 3100
页数:14
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