Dongying City is located in the northeast of Shandong Province and is the central city of the Yellow River Delta. It has abundant oil and gas resources, vast saline-alkali land area, and saline brine as the main groundwater. Therefore, freshwater resources are poor, as there is a contradiction in the water supply and its demand. Judging the trend of sustainable utilization of water resources in Dongying City has an important role in promoting the local conservation and exploitation of water resources, recycling water resources, and undermining the contradiction between supply and demand of urban water resources. In this paper, 21 indicators have been selected to build the index system for judging the sustainable utilization of water resources. In addition, the DPSIR model is used to evaluate the sustainable utilization trend of water resources in Dongying City from 2005 through 2017. On the other hand, the GM (1, 1) model is considered to predict the sustainable potential-utilization of water resources in Dongying City from 2019 through 2025. The results demonstrated that the sustainable utilization of water resources in Dongying City shows an increasing trend from 2005 to 2017, So that the highest and lowest values are in 2017 and 2005, respectively. In addition, the sustainable potential-utilization of water resources in Dongying City may indicate a continuous upward trend from 2019 through 2025. Rainfall, runoff of the Yellow River and water resources per capita are the main factors affecting the sustainable utilization of water resources. According to the continuous improvement of residents' awareness of water saving and water-saving level, the development and exploitation of water resources will be more and more reasonable.