Trends in the incidence of primary liver cancer in Central Uganda, 1960-1980 and 1991-2005

被引:20
|
作者
Ocama, P. [1 ]
Nambooze, S. [2 ]
Opio, C. K. [1 ]
Shiels, M. S. [3 ]
Wabinga, H. R. [2 ]
Kirk, G. D. [3 ]
机构
[1] Makerere Univ, Dept Med, Kampala, Uganda
[2] Makerere Univ, Dept Pathol, Kampala, Uganda
[3] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
基金
美国国家卫生研究院;
关键词
primary liver cancer; hepatocellular carcinoma; cancer registry; Africa; gender differences; human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS); HEPATITIS-C-VIRUS; HEPATOCELLULAR-CARCINOMA; WEST-AFRICA; RISK; HIV; INFECTION; DISEASE; OBESITY; GAMBIA; COHORT;
D O I
10.1038/sj.bjc.6604893
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary liver cancer (PLC) incidence trends from Africa are unknown. Using Kampala Cancer Registry data from 1960 to 1980 and 1991 to 2005, we identified 771 PLCs. Although rates were stable among men, PLC incidence among women increased >50%. Investigations of viral hepatitis, aflatoxin, obesity, and human immunodeficiency virus (HIV) may help to explain the increasing incidence of hepatocellular carcinomas (HCCs).
引用
收藏
页码:799 / 802
页数:4
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