Psoriatic arthritis: latest treatments and their place in therapy

被引:47
|
作者
Kang, Eun Jin [2 ]
Kavanaugh, Arthur [1 ]
机构
[1] Univ Calif San Diego, Div Rheumatol Allergy & Immunol, Ctr Innovat Therapy, La Jolla, CA 92037 USA
[2] Busan Med Ctr, Dept Med, Div Rheumatol, Busan, South Korea
关键词
disease-modifying antirheumatic drugs; immunomodulatory therapies; psoriatic arthritis; ORAL PHOSPHODIESTERASE-4 INHIBITOR; ANTI-INTERLEUKIN-17A MONOCLONAL-ANTIBODY; CHRONIC PLAQUE PSORIASIS; LONG-TERM EXTENSION; CONTROLLED-TRIAL; DOUBLE-BLIND; CLINICAL-EFFICACY; ARTICULAR MANIFESTATIONS; RADIOGRAPHIC PROGRESSION; ADALIMUMAB EFFECTIVENESS;
D O I
10.1177/2040622315582354
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Psoriatic arthritis (PsA) is a heterogeneous chronic inflammatory disease that may affect peripheral and axial joints, entheses, skin and nails, and other organs. Treatment with nonsteroidal anti-inflammatory drugs, steroid and disease-modifying antirheumatic drugs had been the backbone of traditional management of PsA for many years. However, improvement in our understanding of immunopathogenesis of PsA has led to new immunomodulatory therapies. Introduction of novel agents has raised the bar for treatment and helped drive research into additional therapeutic options.
引用
收藏
页码:194 / 203
页数:10
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