TREATMENT OF MULTIDRUG-RESISTANT AND EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS IN ADOLESCENT PATIENTS

被引:5
|
作者
Rodrigues, Magda [1 ]
Brito, Maria [2 ]
Villar, Miguel [3 ]
Correia, Paula [2 ]
机构
[1] Hosp Santa Maria, Dept Paediat, Lisbon, Portugal
[2] Hosp Prof Doutor Fernando Fonseca, Dept Paediat, P-2720276 Amadora, Portugal
[3] Pneumol Diagnost Ctr, Amadora, Portugal
关键词
adolescents; multidrug-resistant tuberculosis; extensively resistant tuberculosis; linezolid; PEDIATRIC-PATIENTS; EFFICACY;
D O I
10.1097/INF.0000000000000341
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The authors describe 2 pediatric patients with drug-resistant tuberculosis in whom new diagnostic and therapeutic approaches were crucial to good clinical evolution. Although there was good clinical outcome, important side effects with linezolid and amikacin occurred, namely medullary hypoplasia and neurosensorial hypoacusia, respectively. A multidisciplinary approach with close follow up was of major importance in managing these patients.
引用
收藏
页码:657 / 659
页数:3
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