New HLA-A*11 allele, A*1112, identified by sequence-based typing

被引：8
|
作者：
Garino, E
Belvedere, M
Berrino, M
Bertola, L
Dall'Omo, AM
Mazzola, G
Rossetto, C
Carcassi, C
Lai, S
Gay, E
Ricotti, M
Curtoni, ES
机构：
[1] S Giovanni Battista Hosp, I-10126 Turin, Italy
[2] Regina Margherita Childrens Hosp OIRM, Turin, Italy
[3] Dept Med Sci, Cagliari, Italy
来源：
TISSUE ANTIGENS | 2002年 / 60卷 / 01期
关键词：
dye terminator cycle sequencing; HLA-A*11; new allele; PCR-SSP; sequencing-based typing;
D O I：
10.1034/j.1399-0039.2002.600111.x
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this report, we describe the identification of HLA-A*1112, a novel HLA-A*11 allele found in two Italian families. The new allele was detected during routine HLA typing by a polymerase chain reaction sequence-specific primer and was confirmed by high-resolution sequencing-based typing. The nucleotide sequences of HLA-A*1112 exons 2 and 3 are identical to HLA-A*11011 except for a single nucleotide substitution in codon 90 (GAC-->GCC).
引用
收藏
页码：84 / 87
页数：4
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