An illustrated clinical update on necrobiosis lipoidica

Necrobiosis lipoidica (NL) is an uncommon granulomatous inflammatory skin problem, which can be associated with diabetes mellitus. NL is often chronic and the lesions typically affect the lower limbs. NL may result in distress and disfigurement, especially in young women. The pathophysiology of NL is currently not well understood. Local and topical treatments remain the mainstay treatment. The ongoing management of recalcitrant NL, especially ulcerating disease remains challenging. Treating physicians of advanced cases need to be aware of the significant psychosocial impacts of this debilitating and sometimes painful skin disease.