Subtype-specific amino acid polymorphisms in the HIV-1 reverse transcriptase connection subdomain of CRF01_AE are associated with higher 3′-azido-3′-deoxythymidine resistance

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作者
Delviks-Frankenberry, K. A. [1 ]
Nikolenko, G. N. [1 ]
Maldarelli, F.
Hase, S. [2 ]
Takebe, Y. [2 ]
Pathak, V. K. [1 ]
机构
[1] NCI, Viral Mutat Sect, Host Virus Interact Branch, HIV Drug Resistance Program, Frederick, MD 21701 USA
[2] Natl Inst Infect Dis, AIDS Res Ctr, Lab Mol Virol & Epidemiol, Tokyo, Japan
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R51 [传染病];
学科分类号
100401 ;
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29
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页码:A31 / A31
页数:1
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  • [1] Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3′-Azido-3′-Deoxythymidine
    Delviks-Frankenberry, Krista A.
    Nikolenko, Galina N.
    Maldarelli, Frank
    Hase, Saiki
    Takebe, Yutaka
    Pathak, Vinay K.
    [J]. JOURNAL OF VIROLOGY, 2009, 83 (17) : 8502 - 8513
  • [2] Mutations in the connection domain of HIV-1 reverse transcriptase increase 3′-azido-3′-deoxythymidine resistance
    Nikolenko, Galina N.
    Delviks-Frankenberry, Krista A.
    Palmer, Sarah
    Maldarelli, Frank
    Fivash, Matthew J., Jr.
    Coffin, John M.
    Pathak, Vinay K.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (01) : 317 - 322
  • [3] 3′-azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes
    Ren, JS
    Esnouf, RM
    Hopkins, AL
    Jones, EY
    Kirby, I
    Keeling, J
    Ross, CK
    Larder, BA
    Stuart, DI
    Stammers, DK
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (16) : 9518 - 9523
  • [4] Subtype-specific differences in transmission cluster dynamics of HIV-1 B and CRF01_AE in New South Wales, Australia
    Di Giallonardo, Francesca
    Pinto, Angie N.
    Keen, Phillip
    Shaik, Ansari
    Carrera, Alex
    Salem, Hanan
    Selvey, Christine
    Nigro, Steven J.
    Fraser, Neil
    Price, Karen
    Holden, Joanne
    Lee, Frederick J.
    Dwyer, Dominic E.
    Bavinton, Benjamin R.
    Geoghegan, Jemma L.
    Grulich, Andrew E.
    Kelleher, Anthony D.
    [J]. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24 (01)
  • [5] Mechanism by which phosphonoformic acid resistance mutations restore 3′-azido-3′-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase
    Arion, D
    Sluis-Cremer, N
    Parniak, MA
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (13) : 9251 - 9255
  • [6] Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside lnhibitors
    Cruchaga, C
    Odriozola, L
    Andréola, M
    Tarrago-Litvak, L
    Martínez-Irujo, JJ
    [J]. BIOCHEMISTRY, 2005, 44 (09) : 3535 - 3546
  • [7] Enhanced NRTI and NNRTI resistance is associated with mutations in the HIV-1 reverse transcriptase connection subdomain of subtype C patients
    Delviks-Frankenberry, K. A.
    Lengruber, R. B.
    Santos, A. F.
    Soares, M. A.
    Kearney, M.
    Maldarelli, F.
    Coffin, J. M.
    Pathak, V. K.
    [J]. ANTIVIRAL THERAPY, 2010, 15 : A78 - A78
  • [8] Phenotypic mechanism of HIV-1 resistance to 3′-azido-3′-deoxythymidine (AZT):: Increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase
    Arion, D
    Kaushik, N
    McCormick, S
    Borkow, G
    Parniak, MA
    [J]. BIOCHEMISTRY, 1998, 37 (45) : 15908 - 15917
  • [9] SYNTHESIS AND HIV-1 REVERSE-TRANSCRIPTASE INHIBITION PROPERTIES OF 2 NEW METHYLENEPHOSPHONATE ANALOGS OF 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE
    LABATAILLE, P
    PELICANO, H
    MAURY, G
    IMBACH, JL
    GOSSELIN, G
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (20) : 2315 - 2320
  • [10] Rapid and Simultaneous Detection of Major Drug Resistance Mutations in Reverse Transcriptase Gene for HIV-1 CRF01_AE, CRF07_BC and Subtype B in China Using Sequenom MassARRAY® System
    Cheung, Ka-Wai
    Peng, Qiaoli
    He, Liufen
    Cai, Kanru
    Jiang, Qiang
    Zhou, Boping
    To, Sabrina Wai-Chi
    Yam, Wing-Cheong
    Liu, Li
    Chen, Zhiwei
    Wang, Hui
    [J]. PLOS ONE, 2016, 11 (04):