Spider neurotoxins as tools for the investigation of glutamate receptors

被引：4
|
作者：
Magazanik, LG
机构：
[1] Sechenov Inst. Evol. Physiol. B., Academy of Sciences of Russia, St.Petersburg, 194223
[2] Laboratory of Biophysics, Sechenov Inst. Evol. Physiol. B., St. Petersburg, 194223
来源：
JOURNAL OF TOXICOLOGY-TOXIN REVIEWS | 1996年 / 15卷 / 01期
关键词：
D O I：
10.3109/15569549609080107
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Progress in the investigation of glutamate receptors structure and function requires the use of specific chemical tools affecting the responses to glutamate and other excitatory amino acids. Several low molecular weight spider and wasp toxins may be used as valuable tools for identification of certain subtypes of glutamate receptors and the study of their function. Some results obtained on different preparations with the help of argiotoxin(-636) (argiopine), neurotoxin isolated from the venom Argiope lobata me reviewed in the present paper.
引用
收藏
页码：59 / 76
页数：18
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