A Suzuki-Miyaura approach to a series of forensically relevant pyridines

被引:17
|
作者
Blachut, Dariusz
Czarnocki, Zbigniew
Wojtasiewicz, Krystyna
机构
[1] Warsaw Univ, Fac Chem, PL-02093 Warsaw, Poland
[2] Int Secur Agcy, Dept Criminalist, PL-02134 Warsaw, Poland
来源
SYNTHESIS-STUTTGART | 2006年 / 17期
关键词
cross-coupling reactions; heterocycles; chemoselectivity; amphetamine analogues; route-specific by-products;
D O I
10.1055/s-2006-942535
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A convenient and general method for the preparation of sixteen 3,5-diarylsubstituted 2,4- and 2,6-dimethylpyri dines of high forensic importance is described. The Suzuki cross-coupling reaction between a range of ring-substituted phenylboronic acids and 3,5-dibromo-2,4-dimethylpyridine and 3,5-dibromo-2,6-dimethylpyridine was used as a key step.
引用
收藏
页码:2855 / 2864
页数:10
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