Cutaneous sarcoidosis successfully treated with topical tacrolimus

被引：45
|
作者：
Katoh, N [1 ]
Mihara, H [1 ]
Yasuno, H [1 ]
机构：
[1] Kyoto Prefectural Univ Med, Dept Dermatol, Kamigyo Ku, Kyoto 6020841, Japan
来源：
BRITISH JOURNAL OF DERMATOLOGY | 2002年 / 147卷 / 01期
关键词：
cutaneous sarcoidosis; immunosuppressive agent; tacrolimus;
D O I：
10.1046/j.1365-2133.2002.04727.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Sarcoidosis is a disorder characterized by macrophage- and T-cell-mediated responses to as yet unidentified infectious antigens or autoantigens. We describe a 62-year-old woman with a 10-year history of orange-yellow plaques of sarcoidosis on her face. Her cutaneous lesions responded to topical tacrolimus ointment after unsuccessful treatment with topical and systemic corticosteroids. No adverse effects were noted with topical tacrolimus in this patient. We discuss the mode of action by which this immunosuppressive agent may act against sarcoidosis.
引用
收藏
页码：154 / 156
页数：3
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