Synthesis and Antimicrobial Activity of Some New Chalcones of 2-Acetyl Pyridine

被引:43
|
作者
Prasad, Y. Rajendra [1 ]
Kumar, P. Praveen [1 ]
Kumar, P. Ravi [1 ]
Rao, A. Srinivasa [1 ]
机构
[1] Andhra Univ, Univ Coll Pharmaceut Sci, Visakhapatnam 530003, Andhra Pradesh, India
关键词
Chalcones; Synthesis; Antimicrobial activity;
D O I
10.1155/2008/602458
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Six new chalcones were synthesised by condensing 2-acetyl pyridine with aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation. All these compounds were characterised by means of their IR, H-1 NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds was evaluated by the cup plate method.
引用
收藏
页码:144 / 148
页数:5
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