SYNTHESIS AND CHARACTERIZATION OF BIOCOMPATIBLE Fe3O4 FOR USE IN CELL HYPERTHERMIA

被引：1
|
作者：
Sampaio da Silva, Fernanda A. [1 ]
Rojas, Edwin E. G. [1 ]
Rodrigues, Girley F. [2 ]
da Silva, Bruno F. A. [3 ]
de Campos, Marcos Flavio [1 ]
机构：
[1] EEIMVR Univ Fed Fluminense, Av Trabalhadores 420, Volta Redonda, RJ, Brazil
[2] USP, Escola Politecn, Hyderabad, Andhra Pradesh, India
[3] Inst Pesquisas Technol, Sao Paulo, SP, Brazil
来源：
20TH BRAZILIAN CONFERENCE ON MATERIALS SCIENCE AND ENGINEERING | 2014年 / 775-776卷
关键词：
magnetism; chitosan; castor oil; hyperthermia; NANOPARTICLES;
D O I：
10.4028/www.scientific.net/MSF.755-776.476
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Malignant tumors are caused by uncontrolled multiplication of cells in the body. It is possible to stop the growth of atypical cells by overheating (hyperthermia). By the magnetization process of magnetite nanoparticles, energy is dissipated as heat (Joule effect), producing increase of temperature. This causes the rupture of cancer cells. In this work, magnetic nanoparticles were synthesized by coprecipitation method and coated by biocompatible material (chitosan or castor oil). The samples showed required characteristics of nanocrystallinity, superparamagnetism and biocompatibility. This was deduced from hysteresis curve, thermal analysis and X-ray Diffraction data. Thus, the nanocomposite exhibits excellent features for use in vivo.
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页码：476 / +
页数：2
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