Natriuretic Peptides in Heart Failure and Acute Coronary Syndrome

被引：36

作者：

Gaggin, Hanna K. ^{[1
]}

Januzzi, James L., Jr. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2014年 / 34卷 / 01期

关键词：

Laboratory medicine; Cardiac markers; Biomarkers; BNP; NT-proBNP; Heart failure; Acute coronary syndrome; Natriuretic peptides; ACUTE MYOCARDIAL-INFARCTION; EMERGENCY-DEPARTMENT PATIENTS; INCREASED PLASMA-LEVELS; ST-SEGMENT ELEVATION; ACUTE DYSPNEA; CHEST-PAIN; VAL-HEFT; SYSTOLIC DYSFUNCTION; RISK STRATIFICATION; VASOACTIVE PEPTIDES;

D O I：

10.1016/j.cll.2013.11.007

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are the gold standard biomarkers in determining heart failure (HF) diagnosis and prognosis. These natriuretic peptides may also be useful in guiding HF management, but further studies are needed before they can be routinely recommended for that purpose. A novel natriuretic peptide biomarker, mid-regional pro atrial natriuretic peptide (MR-proANP), shows promise in determining diagnosis and prognosis in HF patients. BNP and NT-proBNP may be of use in excluding myocardial infarction and to assist in determining prognosis in acute coronary syndrome (ACS). Therapeutic implication of natriuretic peptides in ACS is unclear.

引用

页码：43 / +

页数：17

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