The synthesis and biological evaluation of regioisomeric benzothiazolyl coumarins

被引:17
|
作者
Shivashankar, K.
Kulkarni, Manohar V. [1 ]
Shastri, Lokesh A.
Rasal, Vijaykumar P.
Rajendra, Sandur V.
机构
[1] Karnatak Univ, Dept Postgrad Studies Chem, Dharwad 580003, Karnataka, India
[2] Coll Pharm, Karnataka Liberal Educ Soc, Hubli, India
关键词
4-bromomethylcoumarins; antimicrobial; benzothiazole; coumarin; BENZIMIDAZOLES; DERIVATIVES; AGENTS; ETHERS; BETA;
D O I
10.1080/10426500600614550
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Various 4-aryloxymethylcoumarins have been obtained by the r.t. allylic substitution with formylphenols. These have been further reacted with o-aminothiophenol resulting in the formation of a benzothiazole skeleton. These compounds have been synthesised with a view to study their potential as microbial growth inhibitors. Comparative studies on the spectral and antimicrobial activities have also been carried out.
引用
收藏
页码:2187 / 2200
页数:14
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