Facile and efficient synthesis of 1,3,4-oxadiazolyl 1,8-naphthyridines under microwave irradiation

被引：0
|
作者：
Mogilaiah, K. [1 ]
Babu, H. Sharath [1 ]
Prasad, R. Shiva [1 ]
机构：
[1] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2009年 / 48卷 / 06期
关键词：
1,8-Naphthyridines; 1,3,4-oxadiazoles; iodobenzene diacetate [PhI(OAc)(2); microwave irradiation; solvent-free conditions; ORGANIC-SYNTHESIS; AGENTS;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and convenient method for the synthesis of 1-(5-aryl-[1,3,4]-oxadiazol-2-ylmethyl)-3-(3-trifluromethyl-phenyl)-1H-[1,8]-naphthyridin-2-ones 5, by the oxidation of [2-oxo-3-(3-trifluoromethyl-phenyl)-2H-[1,8]naphthyridin-1-yl]acetic acid arylidenchydrazides 4 with iodobenzene diacetate [Ph](OAc)(2)] under microwave irradiation in solvent-free conditions, is described. The products are obtained in good)Fields and in a state of high purity. The structures of the synthesized compounds have been established on the basis of spectral and analytical data.
引用
收藏
页码：868 / 872
页数：5
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