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RETRACTED: Therapeutic and protective effect of two luminescent 3D Cd(II) compounds on heart failure via high-intensity focused ultrasound (Retracted article. See vol. 1277, 2023)
被引:1
|作者:
Zhao, Li
[1
]
Bian, Rong
[2
]
Chen, Hao
[3
]
机构:
[1] Southwest Univ Hosp, Ultrasound Med Dept, Chongqing 400715, Peoples R China
[2] Seventh Div Hosp Xinjiang Prod & Construct Corps, Cardiol Dept, Kuitun 833200, Xinjiang, Peoples R China
[3] First Peoples Hosp Lanzhou City, Funct Examinat Sect, Lanzhou 730050, Peoples R China
关键词:
Cd(II) compound;
Hydrothermal reaction;
Luminescence;
Heart failure;
METAL-ORGANIC FRAMEWORKS;
COORDINATION POLYMERS;
LIGAND;
D O I:
10.1016/j.molstruc.2022.132411
中图分类号:
O64 [物理化学(理论化学)、化学物理学];
学科分类号:
070304 ;
081704 ;
摘要:
Two Cd(II) compounds, namely, [Cd(pdc)(H2O)](n) (1) and [Cd(pdc)(MeOH)](n )(2) (H(2)pdc = terephthalic acid, MeOH = methanol), were successfully synthesized under the hydrothermal condition of H(2)pdc and Cd(NO3)(2)center dot 4H(2)O in different solvents. Compounds 1 and 2 show intense luminescent emission bands under room temperature. The application values of these compounds on heart failure via high-intensity focused ultrasound was evaluated, and the specific principle was studied. First, enzyme linked immune sorbent assay was conducted, and the number of inflammatory cytokines delivered by the cardiomyocytes was determined. In addition, the relative expression of adhesion molecule-1 in cardiomyocytes was determined via real time RT-PCR after indicated compound treatment. CCK-8 assay was conducted to explore the toxicity of the new compounds. (C) 2022 Elsevier B.V. All rights reserved.
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