Normalization of Hematologic and Health-Related Quality of Life Markers in Patients With Paroxysmal Nocturnal Hemoglobinuria Treated With Pegcetacoplan and Baseline Hemoglobin at or Above 10 g/dL

被引：0
|
作者：
Desai, Dharmik [1 ]
Panse, Jens [2 ]
Daguindau, Nicolas [3 ]
Okuyama, Sonia [4 ]
de Latour, Regis Peffault [5 ,6 ]
Schafhausen, Philippe [7 ]
Straetmans, Nicole [8 ]
Al-Adhami, Mohammed [1 ]
Ajayi, Temitayo [1 ]
Persson, Emmelie [9 ]
Yeh, Michael [1 ]
Wong, Raymond [10 ,11 ]
机构：
[1] Apellis Pharmaceut Inc, Waltham, MA USA
[2] Univ Hosp RWTH Aachen, Dept Hematol Oncol Hemostaseol & Stem Cell Transp, Aachen, Germany
[3] Ctr Hosp Annecy Genevois, Epagny Metz Tessy, France
[4] Denver Hlth & Hosp Author, Div Hematol Oncol, Denver, CO USA
[5] Assistance Publ Hop Paris, French Reference Ctr Aplast Anemia & Paroxysmal N, Paris, France
[6] Univ Paris, Paris, France
[7] Univ Med Ctr Hamburg Eppendorf, Med Clin & Polyclin 2, Hematol Oncol, Hamburg, Germany
[8] Clin Univ St Luc, Dept Hematol, Woluwe St Lambert, Belgium
[9] Swedish Orphan Biovitrum AB, Stockholm, Sweden
[10] Chinese Univ Hong Kong, Prince Wales Hosp, Sir YK Pao Ctr Canc, Hong Kong, Peoples R China
[11] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Hong Kong, Peoples R China
来源：
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2022年 / 22卷
关键词：
MDS; paroxysmal nocturnal hemoglobinuria (PNH); normalization; pegcetacoplan; hemoglobin; complement inhibitor; Phase III;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
MDS-112
引用
收藏
页码：S305 / S305
页数：1
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    Tapia, Jose
    Panse, Jens
    Daguindau, Nicolas
    Okuyama, Sonia
    de Latour, Regis Peffault
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    Straetmans, Nicole
    Al-Adhami, Mohammed
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    Persson, Emmelie
    Yeh, Michael
    Wong, Raymond Siu Ming
    [J]. ANESTHESIA AND ANALGESIA, 2022, 135 (3S_SUPPL): : 19 - 20
  • [2] Normalization of Hemoglobin, Lactate Dehydrogenase, and Fatigue in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Pegcetacoplan
    Mulherin, Brian P.
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    [J]. DRUGS IN R&D, 2024, 24 (02) : 169 - 177
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    de latour, Regis Peffault
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    Al-Adhami, Mohammed
    Ajayi, Temitayo
    Yeh, Michael
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2022, 197 : 135 - 136
  • [4] Pegcetacoplan treatment in patients with paroxysmal nocturnal hemoglobinuria and baseline hemoglobin levels at or above 10 grams per deciliter: A post hoc analysis
    Panse, J.
    Daguindau, N.
    Okuyama, S.
    de latour, R. Peffault
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    [J]. BONE MARROW TRANSPLANTATION, 2022, 57 (SUPPL 1) : 247 - 248
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    [J]. ANESTHESIA AND ANALGESIA, 2022, 135 (3S_SUPPL): : 11 - 12
  • [6] Health-Related Quality of Life Reported Among Patients with Paroxysmal Nocturnal Hemoglobinuria: Impact of Treatment with Pegcetacoplan and C5-Inhibitors
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    [J]. PLOS ONE, 2024, 19 (07):
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    [J]. ACTA HAEMATOLOGICA, 2024,
  • [10] Post Hoc Analysis of the Effect of Pegcetacoplan Treatment of Patients with Paroxysmal Nocturnal Hemoglobinuria and Baseline Hemoglobin Levels Greater Than 10 Grams per Deciliter
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    [J]. BLOOD, 2021, 138
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