Light-based technologies for management of COVID-19 pandemic crisis

被引：57

作者：

Sabino, Caetano P. ^{[1
,2
]}

Ball, Anthony R. ^{[3
]}

Baptista, Mauricio S. ^{[4
]}

Dai, Tianhong ^{[5
,6
]}

Hamblin, Michael R. ^{[5
,7
]}

Ribeiro, Martha S. ^{[8
]}

Santos, Ana L. ^{[3
,9
,10
]}

Sellera, Fabio P. ^{[11
,12
]}

Tegos, George P. ^{[3
,13
]}

Wainwright, Mark ^{[14
]}

机构：

[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Clin Anal, Sao Paulo, SP, Brazil

[2] BioLambda Sci & Commercial LTD, Sao Paulo, SP, Brazil

[3] GAMA Therapeut LLC, Massachusetts Biomed Initiatives, Worcester, MA USA

[4] Univ Sao Paulo, Inst Chem, Dept Biochem, Sao Paulo, SP, Brazil

[5] Harvard Med Sch, Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02115 USA

[6] Harvard Med Sch, Massachusetts Gen Hosp, Vaccine & Immunotherapy Ctr, Boston, MA 02115 USA

[7] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, Doornfontein, South Africa

[8] Natl Commiss Nucl Energy, Ctr Lasers & Applicat, Nucl & Energy Res Inst, Sao Paulo, SP, Brazil

[9] Rice Univ, Dept Chem, Houston, TX USA

[10] IdISBA Fdn Invest Sanitaria Islas Baleares, Palma De Mallorca, Spain

[11] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Internal Med, Sao Paulo, SP, Brazil

[12] Univ Metropolitana Santos, Sch Vet Med, Santos, SP, Brazil

[13] Micromoria LLC, Marlborough, MA USA

[14] Liverpool John Moores Univ, Sch Pharm & Biomol Sci, Liverpool, Merseyside, England

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 2020年 / 212卷

基金：

美国国家卫生研究院; 巴西圣保罗研究基金会;

关键词：

photoinactivation; ultraviolet; photodynamic; photobiomodulation; germicidal; virucidal; photobiology; ULTRAVIOLET GERMICIDAL IRRADIATION; LEVEL LASER THERAPY; ACUTE LUNG INFLAMMATION; PHOTODYNAMIC INACTIVATION; BLUE-LIGHT; METHYLENE-BLUE; PSEUDOMONAS-AERUGINOSA; VIRUS INACTIVATION; IN-VITRO; PHOTOINACTIVATION;

D O I：

10.1016/j.jphotobiol.2020.111999

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The global dissemination of the novel coronavirus disease (COVID-19) has accelerated the need for the implementation of effective antimicrobial strategies to target the causative agent SARS-CoV-2. Light-based technologies have a demonstrable broad range of activity over standard chemotherapeutic antimicrobials and conventional disinfectants, negligible emergence of resistance, and the capability to modulate the host immune response. This perspective article identifies the benefits, challenges, and pitfalls of repurposing light-based strategies to combat the emergence of COVID-19 pandemic.

引用

页数：8

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