Genetic Studies on Noise-Induced Hearing Loss: A Review

被引：103

作者：

Konings, Annelies ^{[1
]}

Van Laer, Lut ^{[1
]}

Van Camp, Guy ^{[1
]}

机构：

[1] Univ Antwerp, Dept Med Genet, B-2610 Antwerp, Belgium

来源：

EAR AND HEARING | 2009年 / 30卷 / 02期

关键词：

TEMPORARY THRESHOLD SHIFT; PRODUCT OTOACOUSTIC EMISSIONS; LANGE-NIELSEN-SYNDROME; ORAL MAGNESIUM INTAKE; COCHLEAR BLOOD-FLOW; PIG INNER-EAR; POTASSIUM CHANNEL; ACOUSTIC TRAUMA; HAIR-CELLS; GUINEA-PIG;

D O I：

10.1097/AUD.0b013e3181987080

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

Millions of people are exposed daily to harmful levels of noise in their work environment. This renders noise-induced hearing loss (NIHL) one of the most important occupational health hazards. Beside age-related hearing loss, NIHL is the second most frequent form of hearing loss. It is a complex condition that is influenced by both environmental factors and genetic factors. Association studies have identified the first genetic factors that may influence one's susceptibility to NIHL. In this review, we discuss the general properties of NIHL and mainly focus on the results of these first genetic association studies for NIHL.

引用

页码：151 / 159

页数：9

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