Antiinflammatory Drugs, Anticoagulation, and Upper Gastrointestinal Bleeding

被引：17
|
作者：
Lee, Mindy Winghin [1 ]
Katz, Philip O. [1 ]
机构：
[1] Weill Cornell Med Coll, Div Gastroenterol & Hepatol, 1315 York Ave,First Floor, New York, NY 10021 USA
来源：
CLINICS IN GERIATRIC MEDICINE | 2021年 / 37卷 / 01期
关键词：
Nonsteroidal antiinflammatory drugs (NSAIDs); Anticoagulation; Elderly Upper GI bleeding; Peptic ulcer disease; PEPTIC-ULCER DISEASE; HIGH-RISK PATIENTS; LOW-DOSE ASPIRIN; SMALL-BOWEL; FOCUSED-UPDATE; GASTRODUODENAL ULCERS; ANTIPLATELET THERAPY; ORAL ANTICOAGULANTS; ATRIAL-FIBRILLATION; PREVENTION;
D O I：
10.1016/j.cger.2020.08.004
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Advanced age, history of peptic ulcer disease, Helicobacter pylori, coadministration of nonsteroidal antiinflammatory drugs (NSAIDs), corticosteroids, anticoagulation, and antiplatelets are risk factors for gastrointestinal bleeding in the elderly. Awareness of these risks and appropriate use of NSAIDs, particularly in those needing antiplatelet or anticoagulant therapy, is critical to optimal management. Careful selection of elderly patients requiring antiplatelet, anticoagulation, or chronic NSAID therapy for cotherapy with proton pump inhibitors can significantly reduce morbidity and mortality from gastrointestinal bleeding. © 2020 Elsevier Inc.
引用
收藏
页码：31 / 42
页数：12
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