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Cytotoxic Triterpenoids from the Rhizomes of Astilbe chinensis
被引:12
|作者:
Cai, Xing-Fu
[1
]
Park, Bo-Young
[1
]
Ahn, Kyung-Seop
[1
]
Kwon, Ok-Kyoung
[1
]
Lee, Hyeong-Kyu
[1
]
Oh, Sei-Ryang
[1
]
机构:
[1] Korea Res Inst Biosci & Biotechnol, Immune Modulator Res Ctr, Taejon 305806, South Korea
来源:
关键词:
HELA-CELLS;
ACID;
APOPTOSIS;
INDUCTION;
D O I:
10.1021/np900028v
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.
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页码:1241 / 1244
页数:4
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