Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cell Administration (REALIST-COVID) Phase 2 Randomised Controlled Trial

被引：0
|
作者：
Gorman, E. [1 ]
McAuley, D. F. [1 ]
Rostron, A. J. [2 ]
Shankar-Hari, M. [3 ]
Bannard-Smith, J. [4 ]
Bentley, A. M. [5 ]
Brealey, D. [6 ]
Campbell, C. [7 ]
Curley, G. [8 ]
Clarke, M. [7 ]
Dushianthan, A. [9 ]
Hopkins, P. [10 ]
Jackson, C.
Kefala, K. [11 ]
Krasnodembskaya, A. [1 ]
Laffey, J. G. [12 ]
McDowell, C.
McFarland, M. [13 ]
McFerran, J.
McGuigan, P. [13 ]
Perkins, G. D. [14 ]
Silversides, J.
Smythe, J. [15 ]
Thompson, J. [16 ]
Tunnicliffe, W. S. [17 ]
Welters, I. D. M. [18 ]
Williams, B.
O'Kane, C. M. [1 ]
机构：
[1] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast, Antrim, North Ireland
[2] Sunderland Royal Hosp, Crit Care Dept, Sunderland, England
[3] Guys & St Thomas NHS Fdn Trust, Dept Crit Care Med, London, England
[4] Manchester Royal Infirm, Dept Crit Care, Manchester, Lancs, England
[5] Wythenshawe Hosp, Acute Intens Care Unit, Manchester, Lancs, England
[6] Univ Coll London Hosp, London, England
[7] Northern Ireland Clin Trials Unit, Belfast, Antrim, North Ireland
[8] Royal Coll Surgeons Ireland, Dublin, Ireland
[9] Southampton Univ Hosp, Dept Intens Care, Southampton, Hants, England
[10] Kings Coll Hosp London, Kings Trauma Ctr, London, England
[11] Royal Infirm Edinburgh NHS Trust, Dept Crit Care, Edinburgh, Midlothian, Scotland
[12] Natl Univ Ireland Galway, Regenerat Med Inst REMEDI, CURAM Ctr Res Med Devices, Galway, Ireland
[13] Belfast Hlth & Social Care Trust, Belfast, Antrim, North Ireland
[14] Univ Hosp Birmingham, Crit Care Unit, Birmingham, W Midlands, England
[15] NHS Blood & Transplant, Oxford, England
[16] NHS Blood & Transplant, Birmingham, W Midlands, England
[17] Queen Elizabeth Hosp Birmingham, Birmingham, W Midlands, England
[18] Royal Liverpool Univ Hosp, Intens Care Unit, Liverpool, Merseyside, England
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2022年 / 205卷
基金：
英国惠康基金;
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A5285
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial)
    Gorman, Ellen A.
    Rynne, Jennifer
    Gardiner, Hannah J.
    Rostron, Anthony J.
    Bannard-Smith, Jonathan
    Bentley, Andrew M.
    Brealey, David
    Campbell, Christina
    Curley, Gerard
    Clarke, Mike
    Dushianthan, Ahilanadan
    Hopkins, Phillip
    Jackson, Colette
    Kefela, Kallirroi
    Krasnodembskaya, Anna
    Laffey, John G.
    McDowell, Cliona
    McFarland, Margaret
    McFerran, Jamie
    McGuigan, Peter
    Perkins, Gavin D.
    Silversides, Jonathan
    Smythe, Jon
    Thompson, Jacqui
    Tunnicliffe, William S.
    Welters, Ingeborg D. M.
    Amado-Rodriguez, Laura
    Albaiceta, Guillermo
    Williams, Barry
    Shankar-Hari, Manu
    McAuley, Daniel F.
    O'Kane, Cecilia M.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 208 (03) : 256 - 269
  • [2] Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial
    Gorman, Ellen
    Shankar-Hari, Manu
    Hopkins, Phil
    Tunnicliffe, William S.
    Perkins, Gavin D.
    Silversides, Jonathan
    McGuigan, Peter
    Jackson, Colette
    Boyle, Roisin
    McFerran, Jamie
    McDowell, Cliona
    Campbell, Christina
    McFarland, Margaret
    Smythe, Jon
    Thompson, Jacqui
    Williams, Barry
    Curley, Gerard
    Laffey, John G.
    Clarke, Mike
    O'Kane, Cecilia
    McAuley, Daniel F.
    [J]. TRIALS, 2020, 21 (01)
  • [3] Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial
    Ellen Gorman
    Manu Shankar-Hari
    Phil Hopkins
    William S. Tunnicliffe
    Gavin D. Perkins
    Jonathan Silversides
    Peter McGuigan
    Colette Jackson
    Roisin Boyle
    Jamie McFerran
    Cliona McDowell
    Christina Campbell
    Margaret McFarland
    Jon Smythe
    Jacqui Thompson
    Barry Williams
    Gerard Curley
    John G. Laffey
    Mike Clarke
    Cecilia O’Kane
    Daniel F. McAuley
    [J]. Trials, 21
  • [4] REPAIR OF ACUTE RESPIRATORY DISTRESS SYNDROME IN COVID-19 BY STROMAL CELLS (REALIST-COVID TRIAL): 1 YEAR FOLLOW UP FOR SAFETY AND PULMONARY DYSFUNCTION
    Gardiner, H. J.
    Gorman, E. A.
    Rostron, A. J.
    Shankar-Hari, M.
    Bannard-Smith, J.
    Bentley, A. M.
    Brealey, D.
    Campbell, C.
    Curley, G.
    Clarke, M.
    Dushianthan, A.
    Hopkins, P.
    Jackson, C.
    Kefela, K.
    Laffey, J. G.
    McDowell, C.
    McFarland, M.
    McFerran, J.
    McGuigan, P.
    Perkins, G. D.
    Silversides, J.
    Smythe, J.
    Thompson, J.
    Tunnicliffe, W. S.
    Welters, I. D. M.
    Williams, B.
    McAuley, D. F.
    O'Kane, C. M.
    [J]. THORAX, 2022, 77 : A30 - A30
  • [5] Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial
    Gorman, Ellen
    Shankar-Hari, Manu
    Hopkins, Phil
    Tunnicliffe, William S.
    Perkins, Gavin D.
    Silversides, Jonathan
    McGuigan, Peter
    Krasnodembskaya, Anna
    Jackson, Colette
    Boyle, Roisin
    McFerran, Jamie
    McDowell, Cliona
    Campbell, Christina
    McFarland, Margaret
    Smythe, Jon
    Thompson, Jacqui
    Williams, Barry
    Curley, Gerard
    Laffey, John G.
    Clarke, Mike
    McAuley, Daniel F.
    O'Kane, Cecilia M.
    [J]. ECLINICALMEDICINE, 2021, 41
  • [6] Mesenchymal stromal cell therapy for COVID-19 acute respiratory distress syndrome: a double-blind randomised controlled trial
    Martinez-Munoz, Maria E.
    Payares-Herrera, Concepcion
    Lipperheide, Ines
    de Molina, Rosa Malo
    Salcedo, Isabel
    Alonso, Rosalia
    Martin-Donaire, Trinidad
    Sanchez, Rocio
    Zafra, Rocio
    Garcia-Berciano, Miguel
    Trisan-Alonso, Andrea
    Perez-Torres, Manuel
    Ramos-Martinez, Antonio
    Ussetti, Piedad
    Rubio, Juan J.
    Avendano-Sola, Cristina
    Duarte, Rafael F.
    [J]. BONE MARROW TRANSPLANTATION, 2024, 59 (06) : 777 - 784
  • [7] MESENCHYMAL STROMAL CELL THERAPY FOR ACUTE RESPIRATORY DISTRESS SYNDROME DUE TO COVID-19
    Brown, Stacey-Ann Whittaker
    Iancu-Rubin, Camelia
    Aboelela, Adam
    Abrahams, Alex
    Burke, Elizabeth
    Drummond, Tiffany
    Grossman, Fred
    Itescu, Silviu
    Lagdameo, Jonathan
    Lin, Jung-Yi
    Mark, Alexis
    Levine, John
    Osman, Keren
    [J]. CRITICAL CARE MEDICINE, 2021, 49 (01) : 77 - 77
  • [8] COVID-19: Mesenchymal stromal cells in acute respiratory distress syndrome?
    Simon, Annika
    [J]. PNEUMOLOGIE, 2023, 77 (09):
  • [9] Acute respiratory distress syndrome in COVID-19
    Dadashzadeh, Nahid
    Farshid, Saman
    Valizadeh, Rohollah
    Nanbakhsh, Mohammad
    Rahimi, Mohsen Mohammad
    [J]. IMMUNOPATHOLOGIA PERSA, 2020, 6 (02):
  • [10] Flow controlled ventilation in Acute Respiratory Distress Syndrome associated with COVID-19: A structured summary of a study protocol for a randomised controlled trial
    Roehrig, Stefan
    Hssain, Ali Ait
    Shallik, Nabil Al Hamid
    Elsaid, Ingi Mohamed A.
    Mustafa, Salma Faisal
    Smain, Osama A. M.
    Molokhia, Ashraf Abdulla
    Lance, Marcus D.
    [J]. TRIALS, 2020, 21 (01)
12345