Sn-based metal-organic framework for highly selective capture of monophosphopeptides

被引:0
|
作者
Xiao, Jing [1 ]
Yang, Shi-Shu [1 ]
Wu, Jian-Xiang [1 ]
Wu, Nan [1 ]
Yu, Xizhong [2 ]
Shang, Wenbin [2 ]
Gu, Zhi-Yuan [1 ]
机构
[1] Nanjing Normal Univ, Coll Chem & Mat Sci, Jiangsu Collaborat Innovat Ctr Biomed Funct Mat, Jiangsu Key Lab Biofunct Mat, Nanjing 210023, Peoples R China
[2] Nanjing Univ Chinese Med, Coll Clin Med 1, Key Lab Metab Dis Chinese Med, Nanjing 210023, Peoples R China
基金
中国国家自然科学基金;
关键词
Metal-organic frameworks monophosphopeptides enrichment mass spectrometry; AFFINITY-CHROMATOGRAPHY; XYLENE ISOMERS; ENRICHMENT; PHOSPHOPEPTIDES; GRAPHENE; MONOPHOSPHORYLATION; PHOSPHOPROTEOME; ADSORPTION; SEPARATION; PROTEINS;
D O I
10.1016/j.talanta.2020.121812
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Sn-based metal-organic framework (MOF) was utilized to effectively capture monophosphopeptides due to the unique affinity. The Sn-based MOF demonstrated the good sensitivity and selectivity in the model phosphoproteins enrichment and was successfully applied in the biological fluids.
引用
收藏
页数:6
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