Cytotoxic Oleanane Triterpene Saponins from Albizia chinensis

被引：37
|
作者：
Liu, Rui [1 ,2 ,3 ]
Ma, Shuanggang [1 ,2 ,3 ]
Yu, Shishan [1 ,2 ,3 ]
Pei, Yuehu [4 ]
Zhang, Sen [1 ,2 ,3 ]
Chen, Xiaoguang [1 ,2 ,3 ]
Zhang, Jianjun [1 ,2 ,3 ]
机构：
[1] Chinese Acad Med Sci, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Beijing 100050, Peoples R China
[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
[3] Peking Union Med Coll, Beijing 100050, Peoples R China
[4] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 04期
关键词：
GLYCOSIDES; JULIBRISSIN; ASSIGNMENT; LEAVES;
D O I：
10.1021/np800576s
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new oleanane-type triterpene saponins, albizosides A-C (1-3), were isolated from the stem bark of Albizia chinensis. Their structures were established by 1D and 2D NMR experiments and chemical methods. Compounds 1-3 showed cytotoxic activity against a small panel of human tumor cell lines as well as hemolytic activity against rabbit erythrocytes.
引用
收藏
页码：632 / 639
页数：8
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