The Effective Targeting of KRASG12C Elusiveness

被引：1
|
作者：
Elez, Filiation Elena [1 ]
Tabernero, Josep [1 ]
机构：
[1] Univ Autonoma Barcelona UAB, Dept Med Oncol, Vall dHebron Inst Oncol VHIO, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain
来源：
CANCER CELL | 2020年 / 38卷 / 06期
关键词：
MECHANISM; KRAS;
D O I：
10.1016/j.ccell.2020.11.012
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Developing therapies to directly target KRAS is challenging. In The New England Journal of Medicine, Hong et al. report a promising KRAS-targeting therapy phase I trial. However, a deeper understanding of the underlying biology of each histological context might well be required to optimize the potential benefit of this class of agents.
引用
收藏
页码：785 / 787
页数：3
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