Rate-dependent changes in atrial action potential duration after short-duration rapid atrial pacing in humans

被引:4
|
作者
Watanabe, I [1 ]
Masaki, R [1 ]
Ohkubo, K [1 ]
Okumura, Y [1 ]
Yamada, T [1 ]
Oshikawa, N [1 ]
Saito, S [1 ]
Ozawa, Y [1 ]
Kanmatsuse, K [1 ]
机构
[1] Nihon Univ, Sch Med, Dept Med 2, Itabashi Ku, Tokyo 1738610, Japan
关键词
atrial fibrillation; electrical remodeling; monophasic action potential;
D O I
10.1253/circj.66.874
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The effect of rapid atrial pacing on the rate adaptation of the atrial action potential duration was studied in humans. The right atrial monophasic action potential (RAMAP) of 5 patients was recorded before and after 30min of rapid atria] pacing. The pacing cycle length (CL) was 146 9ms, the shortest duration at which 1:1 capture was possible. The RAMAP duration at 90% repolarization (RMAPD) was measured. CL-dependent changes in RAMAPD (CL 600 ms-CL 300 ms) before and after rapid atrial pacing were 51.8 +/- 10.7 ms and 30.8 +/- 7.6 ms (p<0.05), respectively.
引用
收藏
页码:874 / 875
页数:2
相关论文
共 50 条
  • [1] Dose and Rate-Dependent Effects of Adenosine on Atrial Action Potential Duration in Humans
    Tebbenjohanns J.
    Schumacher B.
    Pfeiffer D.
    Jung W.
    Lüderitz B.
    Journal of Interventional Cardiac Electrophysiology, 1997, 1 (1) : 33 - 37
  • [2] MECHANISM OF FLECAINIDES RATE-DEPENDENT ACTIONS ON ACTION-POTENTIAL DURATION IN CANINE ATRIAL TISSUE
    WANG, ZG
    FERMINI, B
    NATTEL, S
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1993, 267 (02): : 575 - 581
  • [3] Paroxysmal atrial flutter alters atrial action potential duration response to changes in atrial rate
    Clemo, HF
    Dan, D
    Shepard, RK
    Wood, MA
    Gilligan, DM
    Wenger, E
    Ellenbogen, KA
    CIRCULATION, 1997, 96 (08) : 1294 - 1294
  • [4] Left atrial remodelling after short-duration atrial fibrillation in hypertrophic hearts
    Mattioli, AV
    Bonatti, S
    Zennaro, M
    Monopoli, D
    LeNoci, A
    Mattioli, G
    EUROPEAN HEART JOURNAL, 2003, 24 : 43 - 43
  • [5] Rate-Dependent Flecainide Effects on QRS Duration in Atrial Fibrillation
    Corino, V. D. A.
    Mainardi, L. T.
    Husser, D.
    Bollmann, A.
    COMPUTERS IN CARDIOLOGY 2007, VOL 34, 2007, 34 : 729 - +
  • [6] Rate-dependent changes in monophasic action potential herald atrial fibrillation
    Dixit, S
    Spear, RM
    Bhatta, L
    Kozlowski, LC
    Jalife, J
    Scheinman, MM
    Cheng, J
    CIRCULATION, 1999, 100 (18) : 341 - 341
  • [7] Effect of 60 minutes of rapid atrial pacing on atrial action potential duration in the in-situ canine heart
    Watanabe, I
    Masaki, R
    Nuo, M
    Oshikawa, N
    Okubo, K
    Okumura, Y
    Ohya, T
    Yamada, T
    Saito, S
    Ozawa, Y
    Kanmatsuse, K
    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 2003, 8 (03) : 165 - 171
  • [8] Effect of 60 Minutes of Rapid Atrial Pacing on Atrial Action Potential Duration in the In-Situ Canine Heart
    Ichiro Watanabe
    Riko Masaki
    Min Nuo
    Naohiro Oshikawa
    Kimie Okubo
    Yasuo Okumura
    Toshiyuki Ohya
    Takeshi Yamada
    Satoshi Saito
    Yukio Ozawa
    Katsuo Kanmatsuse
    Journal of Interventional Cardiac Electrophysiology, 2003, 8 : 165 - 171
  • [9] Change of atrial refractory period after short duration of rapid atrial pacing: Regional differences and possible mechanisms
    Lee, SH
    Chen, SA
    Yu, WC
    Cheng, JJ
    Kaun, PL
    Hung, CR
    Chang, MS
    Lin, FY
    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1999, 22 (06): : 927 - 934
  • [10] Direct conversion of atrial flutter to sinus rhythm with low-output, short-duration transesophageal atrial pacing
    Ajisaka, H
    Hiraki, T
    Ikeda, H
    Kubara, I
    Yoshida, T
    Ohga, M
    Imaizumi, T
    CLINICAL CARDIOLOGY, 1997, 20 (09) : 762 - 766