Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension

被引：39
|
作者：
Shen, Zhiying [1 ,2 ,3 ]
Shi, Shuangjiao [2 ,3 ]
Ding, Siqing [2 ,3 ]
Zhong, Zhuqing [2 ,3 ]
机构：
[1] Cent South Univ, Third Xiangya Hosp, Dept Hematol, Changsha, Peoples R China
[2] Cent South Univ, Third Xiangya Hosp, Dept Nursing, Changsha, Peoples R China
[3] Cent South Univ, Third Xiangya Hosp, Clin Nursing Safety Management Reasearch Ctr, Changsha, Peoples R China
来源：
FRONTIERS IN PHARMACOLOGY | 2020年 / 11卷
基金：
中国国家自然科学基金;
关键词：
self-efficacy; medication literacy; medication adherence; hypertension; mediating effect; HEALTH LITERACY; ANTIHYPERTENSIVE MEDICATION; BLOOD-PRESSURE; CARE; DETERMINANTS; HOSPITALIZATION; COMMUNICATION; ASSOCIATION; VALIDATION; EXPERIENCE;
D O I：
10.3389/fphar.2020.569092
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Background: Studies have reported that medication literacy had a positive effect on medication adherence in patients with hypertension. However, little is known about the mechanism underlying this relationship in patients with hypertension. Objective: The purpose of this study was to investigate the mediating effect of self-efficacy between medication literacy and medication adherence. Methods: A total of 790 patients with hypertension were investigated using the Chinese Medication Literacy Scale for Hypertensive Patients (C-MLSHP), the Morisky Medication Adherence Scale-8 (MMAS-8) and the Medication Adherence Self-efficacy Scale-Revision (MASES-R). Hierarchical regression and the bootstrap approach were used to analyze the mediating effect of self-efficacy on the relationship between medication literacy and medication adherence. Results: A total of 60.9% of hypertensive patients were low adherent to their antihypertensive drug regimens. Self-efficacy had a significant positive correlation with medication literacy (r= 0.408, p < 0.001) and medication adherence (r = 0.591, p < 0.001). Self-efficacy accounts for 28.7% of the total mediating effect on the relationship between medication literacy and adherence to antihypertensive regimens for hypertensive patients. Conclusion: More than half of the hypertensive patients in the study were low adherent to antihypertensive regimens. Self-efficacy had a partial significant mediating effect on the relationship between medication literacy and medication adherence. Therefore, it was suggested that hypertensive patients' medication adherence might be improved and driven by increasing self-efficacy. Targeted interventions to improve patients' self-efficacy should be developed and implemented. In addition, health care providers should also be aware of the importance of medication literacy assessment and promotion in patients with hypertension.
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页数：10
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