A highly sensitive dopamine sensor based on a polyaniline/reduced graphene oxide/Nafion nanocomposite

A nanocomposite of polyaniline/reduced graphene oxide (PANI-rGO) was synthesized using a hydrothermal method. The product was characterized by FT-IR, Raman spectra, XRD, SEM and TEM. Then the hybrid material of PANI-rGO and Nafion (PANI-rGO-NF) was prepared and used to modify glassy carbon electrode for the trace determination of dopamine (DA) employing differential pulse voltammetry (DPV). It was found that the hybrid material showed good catalytic activity toward the oxidation of DA, and no response to ascorbic acid (AA) and uric acid (UA) was observed, suggesting a high selectivity of the sensor toward DA. The peak currents were linearly correlated with the concentration of DA in the range from 0.05 mu mol/L to 60.0 (R= 0.996) and 60.0 mu mol/L to 180.0 mu mol/L (R = 0.996) with a detection limit of 0.024 mu mol/L (S/N = 3). The modified electrode also exhibited excellent repeatability and stability. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.