A computationally designed immunogen elicits potent anti-V3 neutralizing antibodies

被引：0
|
作者：
Carrico, C. T. [1 ]
Lagerquist, E. [2 ]
Boni, E. [3 ]
Ban, Y. A. [1 ]
Bretz, C. [3 ]
Ellingson, K. [2 ]
Kalyuzhniy, O. [1 ]
Montefiori, D. [4 ]
Strong, R. [3 ]
Stamatatos, L. [2 ]
Schief, W. [1 ]
机构：
[1] Univ Washington, Seattle, WA 98195 USA
[2] Seattle Biomed Res Inst, Seattle, WA 98109 USA
[3] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
[4] Duke Univ, Durham, NC USA
来源：
RETROVIROLOGY | 2009年 / 6卷
关键词：
Surface Plasmon Resonance; Scaffold Protein; Computational Design; Modeling Platform; Structural Search;
D O I：
10.1186/1742-4690-6-S3-P88
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [1] P05-12. A computationally designed immunogen elicits potent anti-V3 neutralizing antibodies
    CT Carrico
    E Lagerquist
    E Boni
    YA Ban
    C Bretz
    K Ellingson
    O Kalyuzhniy
    D Montefiori
    R Strong
    L Stamatatos
    W Schief
    Retrovirology, 6
  • [2] Structural Characterization of Neutralizing Human Anti-V3 Monoclonal Antibodies 3074 and 268-D
    Burke, V. J.
    Kim, S.
    Williams, C.
    Gorny, M. K.
    Zolla-Pazner, S.
    Kong, X.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 46 - 46
  • [3] BROAD AND POTENT NEUTRALIZATION OF HIV-2/SIV BY ANTI-V3 AND ANTI-V4 MONOCLONAL ANTIBODIES
    Kong, Rui
    Li, Hao
    Lopker, Michael
    Easlick, Juliet
    Shah, Anita
    Decker, Julie
    Bibollet-Ruche, Frederic
    Kiviat, Nancy
    Langedijk, Hans
    Hahn, Beatrice
    Robinson, James
    Kwong, Peter
    Shaw, George
    JOURNAL OF MEDICAL PRIMATOLOGY, 2011, 40 (04) : 255 - 255
  • [4] Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
    Sesterhenn, Fabian
    Galloux, Marie
    Vollers, Sabrina S.
    Csepregi, Lucia
    Yang, Che
    Descamps, Delphyne
    Bonet, Jaume
    Friedensohn, Simon
    Gainza, Pablo
    Corthesy, Patricia
    Chen, Man
    Rosset, Stephane
    Rameix-Welti, Marie-Anne
    Eleouet, Jean-Francois
    Reddy, Sai T.
    Graham, Barney S.
    Riffault, Sabine
    Correia, Bruno E.
    PLOS BIOLOGY, 2019, 17 (02)
  • [5] Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes
    Zolla-Pazner, S.
    Wrin, T.
    Seaman, M. S.
    Yu, X.
    Wood, B.
    Self, S.
    Hioe, C. E.
    RETROVIROLOGY, 2009, 6
  • [6] Anti-V3 Monoclonal Antibodies Display Broad Neutralizing Activities against Multiple HIV-1 Subtypes
    Hioe, Catarina E.
    Wrin, Terri
    Seaman, Michael S.
    Yu, Xuesong
    Wood, Blake
    Self, Steve
    Williams, Constance
    Gorny, Miroslaw K.
    Zolla-Pazner, Susan
    PLOS ONE, 2010, 5 (04):
  • [7] Worldwide epitope prevalence of crystallographically resolved anti-V3 antibodies
    Swetnam, J.
    Zolla-Pazner, S.
    Cardozo, T. J.
    RETROVIROLOGY, 2009, 6
  • [8] Two neutralizing anti-V3 monoclonal antibodies act by affecting different functions of human immunodeficiency virus type 1
    Armstrong, SJ
    McInerney, TL
    McLain, L
    Wahren, B
    Hinkula, J
    Levi, M
    Dimmock, NJ
    JOURNAL OF GENERAL VIROLOGY, 1996, 77 : 2931 - 2941
  • [9] A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice
    Malonis, Ryan J.
    Georgiev, George, I
    Haslwanter, Denise
    VanBlargan, Laura A.
    Fallon, Georgia
    Vergnolle, Olivia
    Cahill, Sean M.
    Harris, Richard
    Cowburn, David
    Chandran, Kartik
    Diamond, Michael S.
    Lai, Jonathan R.
    PLOS PATHOGENS, 2022, 18 (06)
  • [10] Anti-V3/Glycan and Anti-MPER Neutralizing Antibodies, but Not Anti-V2/Glycan Site Antibodies, Are Strongly Associated with Greater Anti-HIV-1 Neutralization Breadth and Potency
    Jacob, Rajesh Abraham
    Moyo, Thandeka
    Schomaker, Michael
    Abrahams, Fatima
    Pujol, Berta Grau
    Dorfman, Jeffrey R.
    JOURNAL OF VIROLOGY, 2015, 89 (10) : 5264 - 5275
12345