mTOR INHIBITOR-BASED IMMUNOSUPPRESSION IS ASSOCIATED WITH A HIGHER FREQUENCY OF IFNγ-PRODUCING EBV-SPECIFIC CD4+ T CELLS AS COMPARED TO mTOR INHIBITOR-FREE THERAPY IN KIDNEY TRANSPLANT PATIENTS

被引：0
|
作者：
Moritz, A. [1 ]
Roch, T. [2 ]
Wehler, P. [2 ]
Stervbo, U. [1 ]
Viebahn, R. [3 ]
Westhoff, T. H. [1 ]
Choi, M. [1 ]
Babel, N. [1 ,2 ]
机构：
[1] Ruhr Univ Bochum, Marien Hosp Herne, Ctr Translat Med, Herne, Germany
[2] Charite Univ Med Berlin, BCRT, Berlin, Germany
[3] Ruhr Univ Bochum, Knappschaftskrankenhaus, Bochum Dept Surg, Bochum, Germany
来源：
TRANSPLANT INTERNATIONAL | 2019年 / 32卷
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中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
V019
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页码：12 / 12
页数：1
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    Weel, JFL
    Bemelman, FJ
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    van Oers, MHJ
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    Shin, B.
    Choi, J.
    Kahwaji, J.
    Ge, S.
    Thomas, D.
    Vo, A.
    Galera, O.
    Villicana, R.
    Peng, A.
    Jordan, S.
    Toyoda, M.
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    Deeks, SG
    Hoh, R
    Grant, RM
    Wrin, T
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    Narvaez, A
    Cesar, D
    Abe, K
    Hanley, MB
    Hellmann, NS
    Petropoulos, CJ
    McCune, JM
    Hellerstein, MK
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    Ribera, E.
    Arrizabalaga, J.
    Lonca, M.
    De lazzari, E.
    Plana, M.
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