Pancreatic islet transplantation in a simultaneous pancreas and kidney transplant recirient - a case report

被引：0

作者：

Golebiewska, Justyna ^{[1
]}

Wolnik, Bogumil ^{[2
]}

Hoffmann, Michal ^{[2
]}

Gorycki, Tomasz ^{[3
]}

Sledzinski, Maciej ^{[4
]}

Golab, Karolina ^{[5
]}

Skowronska, Patrycja ^{[6
]}

Milecka, Anna ^{[7
]}

Skora, Iwona ^{[7
]}

Gulczynski, Jacek ^{[8
]}

Zygowska, Iwona ^{[8
]}

Witkowski, Piotr ^{[5
]}

Moszkowska, Grazyna ^{[9
]}

Bieniaszewska, Maria ^{[6
]}

Szurowska, Edyta ^{[3
]}

Sledzinski, Zbigniew ^{[4
]}

Stefaniak, Tomasz ^{[4
]}

Debska-Slizien, Alicja ^{[1
]}

机构：

[1] Med Univ Gdansk, Dept Nephrol Transplantol & Internal Med, Gdansk, Poland

[2] Med Univ Gdansk, Dept Hypertens & Diabetol, Gdansk, Poland

[3] Med Univ Gdansk, Dept Radiol, Gdansk, Poland

[4] Med Univ Gdansk, Dept Gen Endocrine & Transplant Surg, Gdansk, Poland

[5] Univ Chicago, Transplantat Inst, Chicago, IL 60637 USA

[6] Univ Clin Ctr Gdansk, Cell & Tissue Bank, Gdansk, Poland

[7] Univ Clin Ctr Gdansk, Reg Transplant Coordinat Ctr, Gdansk, Poland

[8] Lab Cell & Tissue Banking & Transplantat CellT, Gdansk, Poland

[9] Med Univ Gdansk, Dept Med Immunol, Gdansk, Poland

来源：

CLINICAL DIABETOLOGY | 2020年 / 9卷 / 05期

关键词：

pancreatic islet transplantation; severe hypoglycaemia; QUALITY-OF-LIFE;

D O I：

10.5603/DK.2020.0034

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Beta cell replacement allows for adequate blood glucose control, reduced progression or even reversal of microvascular complications, and improves the quality of life. Simultaneous pancreas and kidney transplantation is the best therapeutic option for patients with type 1 diabetes and end-stage renal disease resulting from diabetic nephropathy. However, when pancreas transplantation is contraindicated or unavailable, pancreatic islet transplantation is an alternative minimally invasive procedure. We report a patient after earlier simultaneous kidney and pancreas transplantation with a failed pancreas graft, and no option for pancreas retransplantation. In this patient pancreatic islet transplantation was performed. The latter resulted in an improved blood glucose control, restoration of hypoglycaemia awareness, and improved quality of life with stable good function of the kidney allograft.

引用

页码：338 / 343

页数：6

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