The RESTORE trial: What did we learn about multiple sclerosis?

被引:1
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作者
Karceski, Steven
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10.1212/WNL.0000000000000423
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R74 [神经病学与精神病学];
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摘要
In their article MS disease activity in RESTORE: A randomized 24-week natalizumab treatment interruption study,(1) Fox and colleagues carefully evaluated a very specific question: what happens if a specific treatment for multiple sclerosis (MS) is temporarily stopped? To many people, this would seem an unusual question. It does not seem logical. Why would a treatment, if it were working, be stopped? The answer is that some treatments can have long-term side effects. In others, like natalizumab, it has been observed that long-term treatment, which is aimed at the immune system, can cause problems with the way that our bodies respond to certain viruses.
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页码:E155 / E157
页数:3
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