Metastatic Adrenocortical Carcinoma Treated with Sunitinib: A Case Report

被引：22

作者：

Lee, Jeong-Ok ^{[1
]}

Lee, Keun-Wook ^{[1
]}

Kim, Chung-Jong ^{[1
]}

Kim, Yu Jung ^{[1
]}

Lee, Hee Eun ^{[2
]}

Kim, Haeryoung ^{[2
]}

Kim, Jee Hyun ^{[1
]}

Bang, Soo-Mee ^{[1
]}

Kim, Jae-Sung ^{[3
]}

Lee, Jong Seok ^{[1
]}

机构：

[1] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea

[2] Seoul Natl Univ, Bundang Hosp, Dept Pathol, Songnam, South Korea

[3] Seoul Natl Univ, Bundang Hosp, Dept Radiat Oncol, Songnam, South Korea

来源：

JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 2009年 / 39卷 / 03期

关键词：

adrenocortical carcinoma; chemotherapy; sunitinib; MITOTANE; TUMORS;

D O I：

10.1093/jjco/hyn146

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. Palliative chemotherapy can be considered in patients with metastatic disease. Although mitotane- or cisplatin-based chemotherapy regimens are widely used, the effects of these agents have been limited. We have experienced a case that showed a partial response with sunitinib after failure of mitotane-based cytotoxic chemotherapy. The clinical benefit from sunitinib persisted 7.5 months in this case. To our knowledge, this is the first reported case showing the effects of sunitinib on metastatic ACC.

引用

页码：183 / 185

页数：3

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