Topographical analysis of cortical neuronal loss associated with disseminated selective neuronal necrosis and infarction after repeated ischemia

被引：25
|
作者：
Hanyu, S
Ito, U
Hakamata, Y
Nakano, I
机构：
[1] JICHI MED SCH,EXPT MED LAB,MINAMI KAWACHI,TOCHIGI 32904,JAPAN
[2] MUSASHINO RED CROSS HOSP,DEPT NEUROSURG,TOKYO,JAPAN
来源：
BRAIN RESEARCH | 1997年 / 767卷 / 01期
关键词：
cerebral infarction; disseminated selective neuronal necrosis; repeated ischemia; threshold; maturation phenomenon; gerbil;
D O I：
10.1016/S0006-8993(97)00726-9
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A study was carried out of the distribution and density of the neurons remaining in the gerbil cerebral cortex following two 10-min periods of ischemia at either 3-, 5- or 48-h intervals. As the interval between the periods of ischemia increased, the ischemic injury was reduced from severe to milder infarction, and further from more to less intense disseminated selective neuronal necrosis. This model is suitable for studying the mechanisms of transition from selective neuronal necrosis to infarction at the threshold level of infarction. (C) 1997 Elsevier Science B.V.
引用
收藏
页码：154 / 157
页数：4
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