Induction of insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta (C/EBPbeta) by advanced glycation endproducts (AGE) through NF-kappaB signalling in pancreatic beta-cells

被引：0

|

作者：

Seufert, JR ^{[1
]}

Nixdorf, S ^{[1
]}

Roller, J ^{[1
]}

Jakob, F ^{[1
]}

机构：

[1] Univ Wurzburg, Med Poliklin, D-8700 Wurzburg, Germany

来源：

DIABETOLOGIA | 2002年 / 45卷

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暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1219

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页码：A392 / A392

页数：1

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[1] CCAAT/enhancer-binding protein beta (C/EBP beta) is induced by hyperglycemia and inhibits transcription of the rat insulin I gene through interaction with E2A transcription factors
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[3] CCAAT/enhancer-binding protein beta (C/EBP beta) regulates nitric oxide synthase 2 (NOS2) gene expression in mTAL cells.
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[4] Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT enhancer-binding protein beta - Inhibitory interactions with basic helix-loop-helix transcription factor E47
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