Near-infrared light control of membrane potential by an electron donor-acceptor linked molecule

被引:3
|
作者
Takano, Yuta [1 ,2 ,3 ]
Miyake, Kazuaki [4 ]
Sobhanan, Jeladhara [3 ]
Biju, Vasudevanpillai [1 ,3 ]
Tkachenko, Nikolai V. [5 ]
Imahori, Hiroshi [2 ,4 ]
机构
[1] Hokkaido Univ, Res Inst Elect Sci, Kita 20,Nishi 10, Sapporo, Hokkaido 0010020, Japan
[2] Kyoto Univ, Inst Integrated Cell Mat Sci WPI iCeMS, Sakyo Ku, Kyoto 6068501, Japan
[3] Hokkaido Univ, Grad Sch Environm Sci, Kita 10,Nishi 5, Sapporo, Hokkaido 060810, Japan
[4] Kyoto Univ, Grad Sch Engn, Dept Mol Engn, Nishikyo Ku, Kyoto 6158510, Japan
[5] Tampere Univ, Fac Engn & Nat Sci, Korkeakoulunkatu 8, FI-33720 Tampere, Finland
关键词
CHARGE-SEPARATION; OPTICAL CONTROL; ION CHANNELS;
D O I
10.1039/d0cc05326k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Near-infrared (NIR) light control of living cellular activities is a highly desired technique for living cell manipulation because of its advantage of high penetrability towards living tissue. In this study, (pi-extended porphyrin)-fullerene linked molecules are designed and synthesized to achieve NIR light control of the membrane potential. A donor-(pi-extended porphyrin)-acceptor linked molecule exhibited the formation of the charge-separated state with a relatively long lifetime (0.68 mu s) and a moderate quantum yield (27-31%). The hydrophilic trimethylammonium-linked triad molecule successfully altered PC12 cells' membrane potential via photoinduced intramolecular charge separation.
引用
收藏
页码:12562 / 12565
页数:4
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