Developments in ion mobility spectrometry-mass spectrometry

被引：122
|
作者：
Collins, DC
Lee, ML [1 ]
机构：
[1] Weber State Univ, Dept Criminal Justice, Ogden, UT 84408 USA
[2] Brigham Young Univ, Dept Chem & Biochem, Provo, UT 84602 USA
来源：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2002年 / 372卷 / 01期
关键词：
ion mobility spectrometry; mass spectrometry; gas-phase electrophoresis; plasma chromatography;
D O I：
10.1007/s00216-001-1195-5
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Ion mobility spectrometry (IMS) has been used for over 30 years as a sensitive detector of organic compounds. The following is a brief review of IMS and its principles with an emphasis on its usage when coupled to mass spectrometry, Since its inception, IMS has been interfaced with quadrupole, time-of-flight, and Fourier-transform ion cyclotron resonance mass spectrometry. These hybrid instruments have been employed for the analysis of a variety of target analytes, including biomolecules, explosives. chemical warfare degradation products, and illicit drugs.
引用
收藏
页码：66 / 73
页数：8
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