The genetics of Salmonella genomic island 1

被引:154
|
作者
Mulvey, Michael R.
Boyd, David A.
Olson, Adam B.
Doublet, Benoit
Cloeckaert, Axel
机构
[1] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB R3E 3R2, Canada
[2] INRA, Unite BioAgresseurs Sante Environm, F-37380 Nouzilly, France
关键词
antibiotic resistance; DT104; genomic island; pentaresistant; SGI1; virulence;
D O I
10.1016/j.micinf.2005.12.028
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Multi drug-resistant Salmonella enterica serovar Typhimurium phage type DT104, resistant to ampicillin, chloramphenicol/florfenicol, streptomycin, sulfonamides, and tetracycline, has disseminated worldwide. The resistance genes reside on the 43-kb Salmonella genomic island I (SGI1), which is transferable. Drug-resistant variants of SGI1 have been identified in numerous serotypes. Strains harboring SGI1 may be more virulent and have a tendency to rapidly disseminate. Crown Copyright (c) 2006 Published by Elsevier SAS. All rights reserved.
引用
收藏
页码:1915 / 1922
页数:8
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