Lactate Clearance as a Marker of Mortality in Pediatric Intensive Care Unit

被引：26
|
作者：
Munde, A. [1 ]
Kumar, N. [1 ]
Beri, R. S. [1 ]
Puliyel, J. M. [1 ]
机构：
[1] St Stephens Hosp, Dept Pediat, Delhi, India
来源：
INDIAN PEDIATRICS | 2014年 / 51卷 / 07期
关键词：
In-hospital mortality; Lactate clearance; PRISM score; ORGAN FAILURE; HYPERLACTATEMIA; INDICATORS; SEPSIS;
D O I：
10.1007/s13312-014-0448-2
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Objectives: To correlate lactate clearance with Pediatric Intensive Care Unit (PICU) mortality. Methods: 45 (mean age 40.15 mo, 60% males) consecutive admissions in the PICU were enrolled between May 2012 to June 2013. Lactate clearance (Lactate level at admission - level 6 hr later x 100 / lactate level at admission) in first 6 hours of hospitalization was correlated to in-hospital mortality and PRISM score. Results: Twelve out of 45 patients died. 90% died among those with delayed/poor clearance (clearance <30%) compared to 8.5% in those with good clearance (clearance >30%) (P<0.001). Lactate clearance <30% predicted mortality with sensitivity of 75%, specificity of 97%, positive predictive value of 90%, and negative predictive value of 91.42%. Predictability was comparable to PRISM score >30. Conclusion: Lactate clearance at six hours correlates with mortality in the PICU.
引用
收藏
页码：565 / 567
页数：3
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