Everyday cognitive failure and depressive symptoms predict fatigue in sarcoidosis: A prospective follow-up study

被引：36
|
作者：
Hendriks, Celine [1 ,2 ,3 ]
Drent, Marjolein [1 ,3 ,4 ]
De Kleijn, Willemien [1 ,5 ]
Elfferich, Marjon [1 ]
Wijnen, Petal [1 ,6 ]
De Vries, Jolanda [1 ,7 ,8 ]
机构：
[1] ILD Care Fdn Res Team, Ede, Netherlands
[2] Univ Utrecht, Fac Med, Utrecht, Netherlands
[3] St Antonius Hosp, ILD Ctr Excellence, Koekoekslaan 1, NL-3435 CM Nieuwegein, Netherlands
[4] Maastricht Univ, Fac Hlth Med & Life Sci, Dept Pharmacol & Toxicol, Maastricht, Netherlands
[5] Radboud Univ Nijmegen, Dept Psychol & Artificial Intelligence, Nijmegen, Netherlands
[6] Maastricht Univ, Med Ctr, Cent Diagnost Lab, Maastricht, Netherlands
[7] St Elisabeth Hosp Tilburg, Dept Med Psychol, Tilburg, Netherlands
[8] Tilburg Univ, Dept Med & Clin Psychol, Tilburg, Netherlands
来源：
RESPIRATORY MEDICINE | 2018年 / 138卷
关键词：
Anxiety; Cognition; Depressive symptoms; Fatigue; Small fiber neuropathy (SFN); Sarcoidosis; Social support; Quality of life (QoL); QUALITY-OF-LIFE; SMALL-FIBER NEUROPATHY; PSYCHOLOGICAL-FACTORS; EXERCISE CAPACITY; MUSCLE STRENGTH; FIT INDEXES; PULMONARY; ANXIETY; STRESS; ASSOCIATION;
D O I：
10.1016/j.rmed.2017.11.008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Fatigue is a major and disabling problem in sarcoidosis. Knowledge concerning correlates of the development of fatigue and possible interrelationships is lacking. Objective: A conceptual model of fatigue was developed and tested. Methods: Sarcoidosis outpatients (n = 292) of Maastricht University Medical Center completed questionnaires regarding trait anxiety, depressive symptoms, cognitive failure, dyspnea, social support, and small fiber neuropathy (SFN) at baseline. Fatigue was assessed at 6 and 12 months. Sex, age, and time since diagnosis were taken from medical records. Pathways were estimated by means of path analyses in AMOS. Results: Everyday cognitive failure, depressive symptoms, symptoms suggestive of SFN, and dyspnea were positive predictors of fatigue. Fit indices of the model were good. Conclusions: The model validly explains variation in fatigue. Everyday cognitive failure and depressive symptoms were the most important predictors of fatigue. In addition to physical functioning, cognitive and psychological aspects should be included in the management of sarcoidosis patients.
引用
收藏
页码：S24 / S30
页数：7
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