Executive Function and Postural Instability in People with Parkinson's Disease

被引:17
|
作者
Xu, Dong [1 ,2 ,3 ]
Cole, Michael H. [1 ,4 ]
Mengersen, Kerrie [5 ]
Silburn, Peter A. [1 ,6 ]
Qiu, Feng [1 ,2 ,7 ]
Graepel, Cara [1 ,2 ]
Kerr, Graham K. [1 ,2 ]
机构
[1] Queensland Univ Technol, Movement Neurosci Program, Inst Hlth & Biomed Innovat, Kelvin Grove, Qld 4059, Australia
[2] Queensland Univ Technol, Sch Exercise & Nutr Sci, Kelvin Grove, Qld 4059, Australia
[3] Shandong Prov Hosp, Dept Neurol, Jinan 250021, Shandong, Peoples R China
[4] Australian Catholic Univ, Sch Exercise Sci, Brisbane, Qld 4014, Australia
[5] Queensland Univ Technol, Sch Math Sci, Brisbane, Qld 4059, Australia
[6] Univ Queensland, Clin Res Ctr, Brisbane, Qld 4059, Australia
[7] Nanjing Med Univ, Affiliated Nanjing Brain Hosp, Dept Neurol, Nanjing 210029, Jiangsu, Peoples R China
关键词
CLINICAL-TESTS; DUAL TASKING; FALLS RISK; MOBILITY; GAIT; INDIVIDUALS; PERFORMANCE; ATTENTION; DEFICITS; REACH;
D O I
10.1155/2014/684758
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The specific aspects of cognition contributing to balance and gait have not been clarified in people with Parkinson's disease (PD). Twenty PD participants and twenty age-and gender-matched healthy controls were assessed on cognition and clinical mobility tests. General cognition was assessed with the Mini Mental State Exam and Addenbrooke's Cognitive Exam. Executive function was evaluated using the TrailMaking Tests (TMT-A and TMT-B) and a computerized cognitive battery which included a series of choice reaction time (CRT) tests. Clinical gait and balance measures included the Tinetti, Timed Up & Go, Berg Balance, and Functional Reach tests. PD participants performed significantly worse than the controls on the tests of cognitive and executive function, balance, and gait. PD participants took longer on Trail Making Tests, CRT-Location, and CRT-Colour (inhibition response). Furthermore, executive function, particularly longer times on CRT-Distracter and greater errors on the TMT-B, was associated with worse balance and gait performance in the PD group. Measures of general cognition were not associated with balance and gait measures in either group. For PD participants, attention and executive function were impaired. Components of executive function, particularly those involving inhibition response and distracters, were associated with poorer balance and gait performance in PD.
引用
收藏
页数:8
相关论文
共 50 条
  • [1] Cognitive function and postural instability in people with Parkinson's disease
    Xu, D.
    Cole, M.
    Mengersen, K.
    Silburn, P.
    Kerr, G.
    [J]. MOVEMENT DISORDERS, 2013, 28 : S185 - S186
  • [2] Clinimetrics of postural instability in Parkinson’s disease
    B. R. Bloem
    Dennis J. Beckley
    Bob J. van Hilten
    Raymund A. C. Roos
    [J]. Journal of Neurology, 1998, 245 : 669 - 673
  • [3] Clinimetrics of postural instability in Parkinson's disease
    Bloem, BR
    Beckley, DJ
    van Hilten, BJ
    Roos, RAC
    [J]. JOURNAL OF NEUROLOGY, 1998, 245 (10) : 669 - 673
  • [4] Postural instability and falls in Parkinson's disease
    Crouse, Jacob J.
    Phillips, Joseph R.
    Jahanshahi, Marjan
    Moustafa, Ahmed A.
    [J]. REVIEWS IN THE NEUROSCIENCES, 2016, 27 (05) : 549 - 555
  • [5] Postural Instability in Parkinson's Disease: A Review
    Palakurthi, Bhavana
    Burugupally, Sindhu Preetham
    [J]. BRAIN SCIENCES, 2019, 9 (09)
  • [6] Postural instability and falls in Parkinson's disease
    Bloem, BR
    van Vugt, JPP
    Beckley, DJ
    [J]. GAIT DISORDERS, 2001, 87 : 209 - 223
  • [7] The relationship between body composition and postural instability in people with idiopathic Parkinson's disease
    Diab, Abdulkareem
    Hale, Leigh
    [J]. MOVEMENT DISORDERS, 2016, 31 : S31 - S32
  • [8] Increased tremor contributes to postural instability and prospective falls in people with Parkinson's disease
    Kerr, G. K.
    Morrison, S.
    Newell, K.
    Silburn, P.
    [J]. MOVEMENT DISORDERS, 2013, 28 : S136 - S137
  • [9] Executive function in Parkinson's disease
    Kanazawa, A
    Hirotaro, N
    Yoshikuni, M
    [J]. ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 2001, 16 (08) : 705 - 706
  • [10] Ankle proprioception and postural instability in Parkinson's disease
    Teasdale, H.
    Preston, E.
    Spratford, W.
    Waddington, G.
    [J]. MOVEMENT DISORDERS, 2018, 33 : S1 - S1