Alpha-fetoprotein in serum and tumor tissues in dogs with hepatocellular carcinoma

被引：12
|
作者：
Kitao, S
Yamada, T
Ishikawa, T
Madarame, H
Furuichi, M
Neo, S
Tsuchiya, R
Kobayashi, K
机构：
[1] Dobutsu Med Ctr, Osaka 5670034, Japan
[2] Lab Vet Internal Med, Osaka 5670034, Japan
[3] Azabu Univ, Sch Vet Med, Vet Teaching Hosp, Sagamihara, Kanagawa 2298501, Japan
来源：
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION | 2006年 / 18卷 / 03期
关键词：
alpha-fetoprotein; canine hepatocellular carcinoma;
D O I：
10.1177/104063870601800312
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Serumalpha-fetoprotein (AFP) concentrations were measured before and after surgical removal of tumor masses in four dogs with hepatocellular carcinoma (HCC). Localization of AFP was also examined immunohistochemically in tumor tissues. In three cases, the serum AFP concentration was 10 to 20 times higher than that of normal dogs. One to two months after surgery, the serum AFP concentration had decreased to normal range. AFP was localized in the tumor tissues in these three cases. One case, which had a low serum AFP, did not show AFP localization in tumor tissue.
引用
收藏
页码：291 / 295
页数：5
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