Early detection of autism spectrum disorders: emerging symptoms and biomarkers

被引：0

作者：

Gousse, Veronique ^{[1
]}

Amsellem, Frederique ^{[3
]}

Delorme, Richard ^{[2
,3
]}

机构：

[1] Aix Marseille Univ, Lab Psychol Sociale, EA 489, Marseille, France

[2] Hop Robert Debre, AP HP, Serv Psychiat Enfant & Adolescent, Paris, France

[3] Inst Pasteur, Genet Humaine & Fonct Cognit, Paris, France

来源：

BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2016年 / 200卷 / 03期

关键词：

AUTISTIC DISORDER; NEONATAL SCREENING; RISK FACTORS; INFANTS AT-RISK; UNAFFECTED SIBLINGS; FACE; MECHANISMS; CHILDREN; GAZE; ATTENTION; PROGRESS; SIGNS;

D O I：

10.1016/S0001-4079(19)30718-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Early recognition of Autism Spectrum Disorders (ASD) in patients before the age of 24 months significantly enhances the prognosis of affected children. That's why researchers try to identify behavioral and I or neurophysiological precursors in the first months of life of children. Prospective studies are specifically performed in infant siblings at risk of ASD. The longitudinal high-risk sibling studies of ASD follow a cohort of children with an older sibling already diagnosed with ASD. Of these, 10-20 % will be diagnosed with ASD during their third year. This review aims to summarize the clinical and neurophysiological studies investigating early markers associated with the emergence of autistic symptoms in children.

引用

页码：415 / 422

页数：8

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