Update in pediatric optic neuritis

被引:15
|
作者
Collinge, Janine E. [1 ]
Sprunger, Derek T. [1 ]
机构
[1] Indiana Univ Hlth, Dept Pediat Ophthalmol & Adult Strabismus, Indianapolis, IN USA
关键词
childhood; optic neuritis; pediatric; NEUROMYELITIS-OPTICA; OLIGODENDROCYTE GLYCOPROTEIN; MULTIPLE-SCLEROSIS; ANTIBODIES; RISK;
D O I
10.1097/ICU.0b013e3283641b86
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose of reviewPediatric optic neuritis is an uncommon disorder with significant distinctions from its adult counterpart. Recognizing the features of this disorder and the potential association with progressive demyelinating processes is important for patients' evaluation and prognosis.Recent findingsIn the last few years, studies have expanded our understanding of demographic and presenting features for optic neuritis in the pediatric population. Emerging research on biomarkers and optical coherence tomography utility offers potential prognostic value in patient management. In addition, pooled research data have allowed for better understanding of the risks factors for progression from isolated optic neuritis to systemic demyelinating processes, such as multiple sclerosis. Although definitive evidence is lacking, corticosteroids remain the cornerstone of treatment. Various other immunosuppressive therapy studies have also reported success, particularly in refractory cases.SummaryA comprehensive understanding of pediatric optic neuritis and its management remains elusive. A randomized clinical trial would potentially increase our knowledge and benefit the afflicted patients.
引用
收藏
页码:448 / 452
页数:5
相关论文
共 50 条
  • [1] Update on Pediatric Optic Neuritis
    Gise, Ryan A.
    Heidary, Gena
    [J]. CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2020, 20 (03)
  • [2] Update on Pediatric Optic Neuritis
    Ryan A. Gise
    Gena Heidary
    [J]. Current Neurology and Neuroscience Reports, 2020, 20
  • [3] Update on pediatric optic neuritis
    Lock, Jane H.
    Newman, Nancy J.
    Biousse, Valerie
    Peragallo, Jason H.
    [J]. CURRENT OPINION IN OPHTHALMOLOGY, 2019, 30 (06) : 418 - 425
  • [4] Optic Neuritis: An Update Typical and Atypical Optic Neuritis
    Hickman, Simon J.
    Ko, Michael
    Chaudhry, Frasat
    Jay, Walter M.
    Plant, Gordon T.
    [J]. NEURO-OPHTHALMOLOGY, 2008, 32 (05) : 237 - 248
  • [5] An update on optic neuritis
    Kraker, Jessica A.
    Chen, John J.
    [J]. JOURNAL OF NEUROLOGY, 2023, 270 (10) : 5113 - 5126
  • [6] An update on optic neuritis
    Jessica A. Kraker
    John J. Chen
    [J]. Journal of Neurology, 2023, 270 : 5113 - 5126
  • [7] Pediatric optic neuritis
    Lehman, Sharon S.
    Lavrich, Judith B.
    [J]. CURRENT OPINION IN OPHTHALMOLOGY, 2018, 29 (05) : 419 - 422
  • [8] Pediatric optic neuritis
    Akkari, M.
    Laabidi, K.
    Klaa, H.
    Ben Rhouma, H.
    Rouissi, A.
    Kraoua, I.
    Turki, I. Ben Youssef
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 : 574 - 574
  • [9] Pediatric optic neuritis
    Cassidy, L
    Taylor, D
    [J]. JOURNAL OF AAPOS, 1999, 3 (02): : 68 - 69
  • [10] Pediatric Optic Neuritis
    Chang, Melinda Y.
    Pineles, Stacy L.
    [J]. SEMINARS IN PEDIATRIC NEUROLOGY, 2017, 24 (02) : 122 - 128